2025

• Haihambo N, Layiwola D, Blank H, Hurlemann R, Scheele D (2025). Loneliness and social conformity: A predictive processing perspective. Ann N Y Acad Sci, doi: 10.1111/nyas.15324. Online ahead of print.

2024

• De Felice S, Chand T, Croy I, Engert V, Goldstein P, Holroyd C B, Kirsch P, Krach S, Ma Y, Scheele D, Schurz M, Schweinberger S R, Hoehl S, Vrticka P, Relational Neuroscience: insights from hyperscanning research, Neurosci Biobehav Rev doi: 10.1016.

• Kanterman A, Scheele D, Nevat M, Saporta N, Lieberz J, Hurlemann R, Shamay-Tsoory S (2024). Let me in: The neural correlates of inclusion motivation in loneliness. J Affect Disord 15:361:399-408

• Berger R, Hurlemann R, Shamay-Tsoory S, Kanterman A, Brauser M, Gorni J, Luhmann M, Schramm E, Schultz J, Philipsen A, Lieberz J, Scheele D (2024) Oxytocin-augmented modular-based group intervention for loneliness: A proof-of-concept randomized-controlled trial. Psychother Psychosom 93:169-180
• Stevens L, Bregulla M, Scheele D (2024) Out of touch? How trauma shapes the experience of social touch – neural and endocrine pathways. Neurosci Biobehav Rev 159:105595
• Mielacher C, Scheele D, Kiebs M, Schmitt L, Dellert T, Philipsen A, Lamm C, Hurlemann R (2024) Altered reward network responses to social touch in major depression. Psychol Med. 54: 308-316

2023

• Schneider E, Hopf D, Aguilar-Raab C, Scheele D, Neubauer AB, Sailer U, Hurlemann R, Eckstein M, Ditzen B (2023) Affectionate touch and diurnal oxytocin levels: An ecological momentary assessment study. Elife 12: e81241
• Mielacher C, Scheele D, Kiebs M, Schmitt L, Dellert T, Philipsen A, Lamm C, Hurlemann R (2023) Altered reward network responses to social touch in major depression. Psychol Med. 542:308-316
• Coenjaerts M, Adrovic B, Trimborn I, Philipsen A, Hurlemann R, Scheele D (2023). Effects of exogenous oxytocin and estradiol on resting-state functional connectivity in women and men. Sci Rep. 13: 3113
  • Supplementary Information
• Sailer U, Riva F, Lieberz J, Campbell-Meiklejohn, Scheele D, Pfabigan DM (2023). Hungry for compliments? Ghrelin is not associated with neural responses to social rewards or their pleasantness. Front Psychiatry 14:1104305
• Schneider E, Hopf D, Eckstein M, Scheele D, Aguilar-Raab C, Herpertz SC, Grinevich V, Ditzen B (2023). Stress during the COVID-19 Pandemic moderates Pain Perception and Momentary Oxytocin Levels. J Clin Med. 16;126:2333

2022

• Morr M, Noell J, Sassin D, Daniels J, Philipsen A, Becker B, Stoffel-Wagner B, Hurlemann R, Scheele D (2022) Lonely in the Dark: Trauma Memory and Sex-specific Dysregulation of Amygdala Reactivity to Fear Signals. Adv Sci (Weinh).9: e2105336
  • Supplementary Information
• Coenjaerts M, Trimborn I, Adrovic B, Stoffel-Wagner B, Cahill L, Philipsen A, Hurlemann R, Scheele D (2022) Estradiol and oxytocin modulate sex differences in hippocampal reactivity and episodic memory. Neuroimage. 264: 119689
  • Supplementary Information
• Lieberz J, Shamay-Tsoory SG, Saporta N, Kanterman A, Gorni J, Esser T, Kuskova E, Schultz J, Hurlemann R, Scheele D (2022) Behavioral and neural dissociation of social anxiety and loneliness. J Neurosci 42: 2570-2583
• Saporta N, Scheele D, Lieberz J‚ Nevat M, Kanterman A, Hurlemann R, Shamay-Tsoory SG (2022) Altered activation in the action observation system during synchronization in high loneliness individuals. Cereb Cortex 33: 385-402
• Saporta N, Peled-Avron L, Scheele D, Lieberz J‚ Hurlemann R, Shamay-Tsoory SG (2022) Touched by loneliness – How loneliness impacts the response to observed human touch: a tDCS study. Soc Cogn Affect Neurosci 17: 142-150
• Morr M, Liu X, Hurlemann R, Becker B, Scheele D (2022) Chronic loneliness: Neurocognitive mechanisms and interventions. Psychother Psychosom 91: 227-237

2021

• Lieberz J, Shamay-Tsoory SG, Saporta N, Esser T, Kuskova E, Stoffel-Wagner B, Hurlemann R, Scheele D (2021) Loneliness and the social brain: how perceived social isolation impairs human interactions. Adv Sci (Weinh). 8: e2102076
  • Supplementary Information
• Morr M, Lieberz J, Dobbelstein M, Philipsen A, Hurlemann R, Scheele D (2021) Insula reactivity mediates subjective isolation stress in alexithymia. Sci Rep. 11: 15326
  • Supplementary Information
• Coenjaerts M, Pape F, Santoso V, Grau F, Stoffel-Wagner B, Philipsen A, Schultz J, Hurlemann R, Scheele D (2021). Sex differences in economic decision-making: exogenous estradiol has opposing effects on fairness framing in women and men. Eur Neuropsychopharmacol 50: 46-54
  • Supplementary Information
• Saporta N, Scheele D, Lieberz J, Stuhr-Wulff F, Hurlemann R, Shamay-Tsoory SG (2021) Opposing Association of Situational and Chronic Loneliness with Interpersonal Distance. Brain Sci. 11: 1135
• Liu C, Lan C, Li K, Zhou F, Yao S, Xu L, Yang N, Yang J, Yong X, Ma Y, Scheele D, Kendrick KM, Becker B (2021) Oxytocinergic modulation of threat-specific amygdala sensitization in humans is critically mediated by serotonergic mechanisms. Biol Psychiatry Cogn Neurosci Neuroimaging 6: 1081-1089
• Liu C, Xu L, Li J, Zhou F, Yang X, Zheng X, Fu M, Li K, Sindermann C, Montag C, Ma Y, Scheele D, Ebstein RP, Yao S, Kendrick KM, Becker B (2021) Serotonin and early life stress interact to shape brain architecture and anxious avoidant behavior – a TPH2 imaging genetics approach. Psychol Med. 51: 2476-2484
• Marsh N, Scheele D, Postin D, Onken M, Hurlemann R (2021) Eye-tracking reveals a role of oxytocin in attention allocation towards familiar faces. Front Endocrinol 12: 629760
• Quintana DS, Lischke A, Grace S, Scheele D, Ma Y, Becker B (2021) Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research. Mol Psychiatry 26: 80-91

2020

• Maier A, Heinen-Ludwig L, Güntürkün O, Hurlemann R, Scheele D (2020) Childhood maltreatment alters the neural processing of chemosensory stress signals. Front Psychiatry 11:783
  • Supplementary Information
• Kreuder AK, Scheele D Schultz JW, Henning J, Marsh N, Dellert T, Ettinger U, Philipsen A, Babasiz M, Herscheid A, Remmersmann L, Stirnberg R, Stöcker T, Hurlemann R (2020) Common and dissociable effects of oxytocin and lorazepam on the neurocircuitry of fear. Proc Natl Acad Sci USA 117:11781-11787
  • Supplementary Information
• Maier A, Gieling C, Heinen-Ludwig C, Stefan V, Schultz J, Güntürkün O, Becker B, Hurlemann R,Scheele D (2020) Association of Childhood Maltreatment With Interpersonal Distance and Social Touch Preferences in Adulthood. Am J Psychiatry 177: 37-46
  • Supplementary Information
• Lieberz J*, Scheele D*, Spengler FB, Matheisen T, Schneider L, Stoffel-Wagner B, Kinfe MT, Hurlemann R (2020) Kinetics of oxytocin effects on amygdala and striatal reactivity vary between women and men. Neuropsychopharmacology 45: 1134-1140
  • Supplementary Information

2019

• Zhou X, Zimmermann K, Xin F, Zhao W, Derckx R, Sassmannshausen A,Scheele D, Hurlemann R, Weber B, Kendrick KM, Becker B (2019) Cue Reactivity in the Ventral Striatum Characterizes Heavy Cannabis Use, Whereas Reactivity in the Dorsal Striatum Mediates Dependent Use. Biol Psychiatry Cogn Neurosci Neuroimaging 4: 751-762
• Zhao W, Zimmermann K, Zhou X, Zhou F, Fu M, Dernbach C, Scheele D, Weber B, Eckstein M, Hurlemann R, Kendrick KM, Becker B (2019) Impaired cognitive performance under psycho-social stress in cannabis-dependent males is associated with attenuated precuneus activity. J Psychiatry Neurosci 44: 1-10
• Chaudhry SR, Lendvai IS, Muhammad S, Westhofen P, Kruppenbacher J, Scheef L, Boecker H, Scheele D Hurlemann R, Kinfe TM (2019) Interictal assay of peripheral circulating inflammatory mediators in migraine patients under adjunctive cervical non-invasive vagus nerve stimulation: a proof-of-concept study. Brain Stimul 12: 643-651
• Spengler FB*, Scheele D*, Kaiser S, Heinrichs M. Hurlemann R (2019) A protective mechanism against illusory perceptions is amygdala-dependent. J Neurosci 39: 3301-3308
• Boström A, Scheele D, Stoffel-Wagner B, Hönig F, Chaudhry SR, Muhammad S, Hurlemann R, Krauss JK, Lendvai IS, Chakravarthy KV, Kinfe TM (2019) Saliva molecular inflammatory profiling in female migraine patients responsive to adjunctive cervical non-invasive vagus nerve stimulation: the MOXY Study. J Transl Med. 17: 53
• Zimmermann K, Kendrick KM., Scheele D, Dau W, Banger M, Maier W, Weber B, Ma Y, Hurlemann R, Becker B (2019) Altered striatal reward processing in abstinent dependent cannabis users: social context matters. Eur Neuropsychopharmacology 29: 356-364
• Kreuder AK, Wassermann L, Wollseifer M, Ditzen B, Eckstein M, Stoffel-Wagner B, Hennig J, Hurlemann R, Scheele (2019) Oxytocin enhances the pain-relieving effects of social support in romantic couples. Hum Brain Mapp. 40: 242 - 251
  • Supplementary Information
• Gravius N, Chaudhry SR, Muhammad S, Boström A, Gravius S, Randau T, Scheele D, Westhofen P, Kruppenbacher J, Stoffel-Wagner B, Maier C, Weidlich A, Yearwood TL, Chakravarthy KV, Kramer JM, Hurlemann R, Kinfe TM (2019) Selective L4 dorsal root ganglion stimulation evokes pain relief and changes of inflammatory markers: Profiling of saliva and serum molecular patterns. Neuromodulation: 22: 44 - 52
• Maier A*, Scheele D*, Spengler F, Menba T, Mohr F, Güntürkün O, Stoffel-Wagner B, Kinfe T, Maier W, Khalsa S, Hurlemann R (2019) Oxytocin reduces a chemosensory-induced stress bias in social perception. Neuropsychopharmacology 44: 281 - 288
  • Supplementary Information (453.5 kB)
• Eckstein M, Almeida de Minas AC, Scheele D, Kreuder AK, Hurlemann R, Grinevich V, Ditzen B (2019) Oxytocin for learning calm and safety. Int J Psychophysiol 136: 5 - 14
• Scheele D, Zimbal S, Feinstein JS, Delis A, Neumann C, Philipsen A, Hurlemann R (2019) Treatment-resistant depression and ketamine response in a patient with bilateral amygdala damage. Am J Psychiatry 176: 982-986 
  • Supplementary Information
• Scheele D, Lieberz J, Patin A, Engels C, Schneider L, Stoffel-Wagner B, Becker B, Hurlemann R (2019) Trauma disclosure moderates the effects of oxytocin on intrusions and neural responses to fear. Psychother Psychosom. 88: 61 - 63
  • Supplementary Information
• Hurlemann R*, Scheele D*, Kinfe TM, Berger R, Philipsen A, Voncken M, Kuypers KPC, Schruers K (2019) Increased temporal discounting in social anxiety disorder normalizes after oxytocin treatment. Psychother Psychosom. 88: 55 - 57
  • Supplementary Information

2018

• Zhou F, Zimmermann K, Xin F, Scheele D, Dau W, Banger M, Weber B, Hurlemann R, Kendrick KM, Becker B (2018) Shifted balance of dorsal versus ventral striatal communication with frontal reward and regulatory regions in cannabis dependent males. Hum Brain Mapp. 39: 5062 - 5073
• Bolea-Alamanac B, Bailey SJ, Lovick TA,Scheele D, Valentino R (2018) Female psychopharmacology matters! Towards a sex-specific psychopharmacology. J Psychopharmacology 32:125-133
• Lendvai IS, Maier A, Scheele D, Hurlemann R, Kinfe TM (2018) Spotlight on cervical vagus nerve stimulation in patients with primary headache disorders: A Review. J Pain Res. 11: 1613 - 1625
• Patin A, Scheele D, Hurlemann R (2018) Oxytocin and Interpersonal Relationships. Curr Top Behav Neurosci. In R. Hurlemann & V. Grinevich (Eds.), Behav Pharmacology Neuropeptides: Oxytocin (S. 389-420). Cham: Springer Nature.

2017

• Marsh N, Scheele D, Feinstein JS, Gerhardt H, Strang S, Maier W, Hurlemann R (2017) Oxytocin-enforced norm compliance reduces xenophobic outgroup rejection. Proc Natl Acad Sci USA. 114: 9314 - 9319
  • Supplementary Information
• Spengler FB, Schultz J, Scheele D, Essel M, Maier W, Heinrichs M, Hurlemann R (2017) Kinetics and dose-dependency of intranasal oxytocin effects on amygdala reactivity. Biol Psychiatry 82: 885 - 894
  • Supplementary Information
• Kreuder AK*, Scheele D*, Wassermann L, Wollseifer M, Stoffel-Wagner B, Lee M, Hennig J, Maier W, Hurlemann R (2017) How the brain codes intimacy: The neurobiological substrates of romantic touch. Hum Brain Mapp. 38: 4525 - 4534
  • Supplementary Information
• Spengler FB*, Scheele D*, Marsh N, Kofferath C, Flach A, Schwarz S, Stoffel-Wagner B, Maier W, Hurlemann R (2017) Oxytocin facilitates reciprocity in social communication. Soc Cogn Affect Neurosci. 2: 1325 - 1333
  • Supplementary Information
• Hurlemann R, Marsh N, Schultz J, Scheele D (2017) Oxytocin shapes the priorities and neural representations of attitudes and values. Behav Brain Sci. (BBS) 40: e241
• Hurlemann R, Scheele D, Maier W, Schultz J (2017) Oxytocin drives prosocial biases in favor of attractive people. Behav Brain Sci. (BBS) 40: e30
• Bennet A, Hopkins WD, Feldman R, Gazzola V, Giedd J, Lamb MJ, Scheele D, Sheridan MA, Suomi SJ, Tomoda A, Tottenham N (2017) Neural Foundations of Variability in Attachment. In H. Keller & K.A. Bard (Eds.), The Cultural Nature of Attachment: Contextualizing Relationships and Development (S. 245-271). Cambridge, MA: MIT Press.

2016

• Striepens S, Schröter F, Stoffel-Wagner B, Maier W, Hurlemann R, Scheele D(2016) Oxytocin enhances cognitive control of food craving in women. Hum Brain Mapp. 37: 4276 - 4285
  • Supplementary Information
• Eckstein M, Scheele D, Patin A, Preckel K, Becker B, Walther A, Domschke K, Grinevich V, Maier W, Hurlemann R (2016) Oxytocin facilitates Pavlovian fear learning in males. Neuropsychopharmacology 41: 932 - 939
  • Supplementary Information
• Hu Y, Scheele D, Becker B, Voos G, David B, Hurlemann R, Weber B (2016) The effect of oxytocin on third-party altruistic decisions in unfair situations: an fMRI study. Sci Rep. 6: 20236
  • Supplementary Information
• Scheele D, Plota J, Stoffel-Wagner B, Maier W, Hurlemann R (2016) Hormonal contraceptives suppress oxytocin-induced brain reward responses to the partner’s face. Soc Cogn Affect Neurosci 11: 767 - 774
  • Supplementary Information
• Hurlemann R & Scheele D (2016) Dissecting the role of oxytocin in the formation and loss of social relationships. Biol Psychiatry 79: 185 - 193
  • Supplementary Information
• Hurlemann R, Maier W, Scheele D(2016) Interactions of noradrenaline and cortisol and the induction of indelible memories. Behav Brain Sci. (BBS) 39: e213

2015

• Marsh N, Scheele D, Gerhardt H, Strang S, Enax L, Weber B, Maier W, Hurlemann R (2015) The neuropeptide oxytocin induces a social altruism bias. J Neurosci. 35: 15696 - 15701
• Fürst A*, Thron J*, Scheele D, Marsh N, Hurlemann R (2015) The neuropeptide oxytocin modulates consumer brand relationships. Sci Rep 5: 14960
  • Supplementary Information
• Scheele D, Schwering C, Spunt RP, Elison JT, Maier W, Hurlemann R (2015) A human tendency to anthropomorphize is enhanced by oxytocin. Eur Neuropsychopharmacology 25: 1817 - 1823
• Hurlemann R, Arndt S, Schlaepfer TE, Reul J, Maier W,Scheele D (2015) Diminished appetitive startle modulation following targeted inhibition of prefrontal cortex. Sci Rep. 5: 8954
  • Supplementary Information
• Eckstein M, Becker B, Scheele D, Scholz C, Preckel K, Schlaepfer TE, Grinevich V, Kendrick KM, Maier W, Hurlemann R (2015) Oxytocin facilitates the extinction of conditioned fear in humans. Biol Psychiatry 78: 194 - 202
• Feature in Scientific American
• Commentary in Biol Psychiatry (2015) 78: 154 – 155
  • Supplementary Information
• Preckel K*, Scheele D*, Eckstein M, Maier W, Hurlemann R (2015) The influence of oxytocin on volitional and emotional ambivalence. Soc Cogn Affect Neurosci 10: 987 - 993
  • Supplementary Information
• Mielacher C, Scheele D, Hurlemann R (2015) Experimental and therapeutic neuromodulation of emotion and social cognition using non-invasive brain stimulation. Nervenarzt 86: 1500 - 1507

2014

• Scheele D Striepens N, Kendrick KM, Schwering C, Noelle J, Wille A, Schlaepfer TE, Maier W, Hurlemann R (2014) Opposing effects of oxytocin on moral judgment in males and females. Hum Brain Mapp. 35: 6067 - 6076
  • Supplementary Information
• Preckel K*,Scheele D*, Kendrick KM, Maier W, Hurlemann R (2014) Oxytocin faciliatates social approach behavior in women. Front Behav Neurosci 8: 191
  • Supplementary Information
• Scheele D, Kendrick KM, Khouri C, Kretzer E, Stoffel-Wagner B, Güntürkün O, Maier W, Hurlemann R (2014) An oxytocin-induced facilitation of neural and emotional responses to social touch correlates inversely with autism traits. Neuropsychopharmacology 39: 2078 - 2085
• Hot Topic SFN 2014, Washington, DC
  • Supplementary Information
• Eckstein M*, Scheele D*, Weber K, Stoffel-Wagner B, Maier W, Hurlemann R (2014) Oxytocin facilitates the sensation of social stress. Hum Brain Mapp. 35: 4741 - 4750

2013

• Scheele D, Wille A, Kendrick KM, Stoffel-Wagner B, Becker B, Güntürkün O, Maier W, Hurlemann R (2013) Oxytocin enhances brain reward system responses in men viewing the face of their female partner. Proc Natl Acad Sci USA 110: 20308 - 20313
• Research Highlight: Nature (2013) 504: 11
  • Supplementary Information
• Scheele D*, Mihov Y*, Schwederski O, Maier W, Hurlemann R (2013) A negative emotional and economic judgment bias in major depression. Eur Arch Psychiatry Clin Neurosci. 263: 675 - 683
• Becker B, Scheele D, Moessner R, Maier W, Hurlemann R (2013) Deciphering the neural signature of conversion blindness. Am J Psychiatry 170: 121 - 122

2012

• Scheele D*, Striepens E*, Güntürkün O, Deutschländer S, Maier W, Kendrick KM, Hurlemann R (2012) Oxytocin modulates social distance between males and females. J Neurosci 32: 16074 - 16079
• Research Highlight: Nature (2012) 492: 157
• Striepens N*,Scheele D*, Kendrick KM, Becker B, Schaefer L, Schwalba K, Reul J, Maier W, Hurlemann R (2012) Oxytocin facilitates protective responses to aversive social stimuli in males. Proc Natl Acad Sci. USA 109: 18144 - 18149
  • Supplementary Information
• Becker B*, Mihov Y*, Scheele D*, Kendrick KM, Feinstein JS, Matusch A, Aydin M, Reich H, Urbach H, Oros-Peusquens AM, Shah NJ, Kunz WS, Schlaepfer TE, Zilles K, Maier W, Hurlemann R (2012) Fear processing and social networking in the absence of a functional amygdala. Biol Psychiatry 72: 70 - 77 (524.3 kB)
  • Supplementary Information
• Brüne M*, Scheele D*, Heinisch C, Tas C, Wischniewski J, Güntürkün O (2012) Empathy moderates the effect of repetitive transcranial magnetic stimulation of the right dorsolateral prefrontal cortex on costly punishment. PLoS One 7:e44747
• Scheele D, Mihov Y, Kendrick KM, Feinstein JS, Reich H, Maier W, Hurlemann R (2012) Amygdala lesion profoundly alters altruistic punishment. Biol Psychiatry 72: e5 - e7

2011

• Krogias C, Hoffmann K, Eyding J, Scheele D, Norra C, Gold R, Juckel G, Assion HJ (2011) Evaluation of basal ganglia, brainstem raphe and ventricles in bipolar disorder by transcranial sonography. Psychiatry Res. 194:190-197

2010

• Edel MA, Rudel A, Hubert C, Scheele D, Brüne M, Juckel G, Assion HJ (2010) Alexithymia, emotion processing and social anxiety in adults with ADHD. Eur J Med Res. 15:403-409
• Studentkowski G, Scheele D, Calabrese P, Balkau F, Höffler J, Aubel T, Edel MA, Juckel G, Assion HJ (2010) Cognitive impairment in patients with a schizoaffective disorder: a comparison with bipolar patients in euthymia. Eur J Med Res. 15: 70-78